十一月 14, 2024

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2024.11.02 l 國際外泌體前瞻研究及創新治療論壇 Featured

Extracellular vesicles (EVs) are lipid bilayer-enclosed particles released by all cell types, ranging in size from 20 nanometers to 10 microns. EVs are categorized into small EVs (sEVs) (<200 nm) and large EVs (lEVs) (>200 nm). Their composition varies depending on their cell of origin and includes proteins, lipids, nucleic acids, metabolites, and organelles. EVs are classified into various subtypes, such as ectosomes, microvesicles, and exosomes, based on their biogenesis. They play diverse biological roles, such as eliminating unwanted materials, transferring proteins and nucleic acids, recycling molecules, signaling, and aiding in cancer metastasis.


In recent years, biomedical research globally and in Taiwan has made significant strides, particularly in developing and applying EVs technology since EVs involved in aging, inflammation, coagulation, disease progression, T cell longevity, and serve as potential biomarkers. Modern biomedical research demands interdisciplinary collaboration and knowledge sharing, with close interaction between different fields now essential for advancing exosome research and its applications. At the upcoming International Forum of Extracellular Vesicles Technology and Novel Therapeutics, participants will explore the latest advancements in exosome technology and its applications in various diseases, driving forward scientific progress in this field.

Time Theme Title Speaker Moderator
08:00~08:30 Registration
08:30~08:40 Opening Ceremony Chang-Hai Tsai
08:40~09:30 Keynote Speech Exosomes and tubular connections in membrane repair and intercellular traffic of proteins and RNA Randy Wayne Schekman Mien-Chie Hung
09:30~09:40 Group Photo 
09:40~10:10 Frontier Insights Effects of extracellular vesicles on immune checkpoint and vector development for EVs to target tumor cells Mien-Chie Hung Der-Yang Cho 
10:10~10:30 Break
10:30~11:00 Pioneered Trends Transitioning EV isolation from the bench to the bedside Andreas Möller Pin-Kuang Charles Lai 
11:00~11:30 HLA-G targeted exosome and its application Jennifer Ho
11:30~12:00 Extracellular Vesicles as a vehicle to deliver CRISPR machinery for gene therapy Houjian Cai
12:00~13:20 Lunch
13:20~13:45 Advanced Development Untangling the Networks of Big and Small Extracellular Vesicle In Vivo Pin-Kuang Charles Lai Tzou-Yien Lin /
Long-Bin Jeng
13:45~14:10 Engineering Extracellular Vesicles for Therapeutic Delivery Le Thi Nguyet Minh
14:10~14:35 CD3ɛ Nanobody-Engineered Extracellular Vesicles Driving in vivo Generation of Dual-Targeting CAR-Ts for Solid Tumor Treatment Shi-Wei Huang
14:35~15:00 Role of STAT3-FOXO3 signaling in the modulation of neuroplasticity by PD-L1-HGF-decorated mesenchymal stem cell-derived exosomes in a murine stroke model Woei-Cheang Shyu
15:00~15:25 Rab37 mediates exosomal osteopontin secretion to promote pancreatic cancer metastasis and stemness Yan-Shen Shan
15:25~15:40 Break
15:40~16:05 Ecosystem Telomerized MSCs as standardized cell factories for EV production and engineering Johannes Grillari Chih-Hung Chang
16:05~16:30 Engineered extracellular vesicles for disease treatments Chi-Ying F. Huang
16:30~16:50 Development of a Targeted Delivery Platform and Manufacturing Process for Drug-Encapsulated Extracellular Vesicles YiWen Chen
16:50~17:00 Closing
17:00 Meeting Adjourn
https://spotlights.cmu.edu.tw/iEVTT/webpage.php?id=7
日期 & 時間
2024.11.02
Last modified on 週三, 23 十月 2024 01:56